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Biodefense in the Intelligence Age
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Market signal
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Research
arXiv
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Launch rankings
Product Hunt-style discovery for AI tools, models, agents, APIs, and open-source releases.
Product Hunt / 1,133 votes
AI fundraising agent that finds investors and books meetings
View launchProduct Hunt / 912 votes
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Media feed
An action plan for AI-powered biological resilience
ChatGPT introduces a new memory system to better remember preferences, keeping context fresh and relevant across conversations.
OpenAI outlines its public policy agenda for AI, including safety, youth protection, workforce transition, and global standards to ensure AI benefits society.
Research corner
As foundation models advance and agent scaffolding becomes increasingly sophisticated, agents have demonstrated remarkable proficiency in complex, long-horizon coding tasks and even autonomous experiment execution. Despite their evolution from research assistants into autonomous research agents, these systems still exhibit significant limitations in field sensitivity, research ethics, and nuanced scientific judgment. Consequently, frontier agents remain unable to fully replace human researchers. To bridge this gap, we conceptualize the AARR (Act As a Real Researcher) benchmark series. Unlike existing benchmarks that primarily assess macro-level execution capabilities, AARR focuses on whether
Pre-layout design space exploration (DSE) for high-speed signal integrity (SI) analysis is often limited by the computational cost of simulations and iterative optimization algorithms within modern electronic design automation (EDA) workflows. While machine learning surrogate models accelerate the simulation step, optimizing designs still requires utilizing iterative black-box search methods. This iterative nature scales poorly, making multi-corner sweeps computationally expensive. As a solution, this paper proposes amortized neural optimization (ANO) for pre-layout SI design. ANO entirely eliminates iterative black-box inference by utilizing fully differentiable neural network surrogate mod
Monolithic vision-action models represent an emerging paradigm in autonomous driving. However, this architecture produces token sequences that quickly exceed real-time computational budgets when encoding extended temporal context for complex interactions. While approaches like linear transformers and external memory try to make the context lightweight, token compression is most compatible with the architecture as it requires no backbone modifications. Yet existing compression adopts rule-based heuristics like temporal decay, decoupled from planning, risking loss of decision-critical information. We propose COMPACT-VA, a planning-aligned working memory framework built on conditional VQ-VAE, c
Whisper, a widely adopted ASR model, is known to suffer from hallucinations - coherent transcriptions generated for non-speech audio entirely disconnected from the input. We investigate whether hallucinations can be detected and mitigated through Whisper's internal representations. We extract audio encoder activations and evaluate two representation spaces: raw Whisper activations and Sparse AutoEncoder (SAE) latents. We show that both spaces encode linearly separable hallucination-related information, with discriminative power concentrated in a sparse feature subset and increasing toward deeper encoder layers. We propose two steering strategies: activation-space steering and SAE latent-spac
Node classification in graph neural networks (GNNs) has been widely applied in various fields of graph analysis. GNNs achieve high-accuracy node classification in homophilous graphs, where nodes with the same class label tend to be connected. However, their performance remains limited in heterophilous graphs, where nodes with different class labels are more likely to be connected. In particular, current GNNs derived from graph convolutional networks cannot capture higher-order class label connectivity, which is frequently observed in real-world heterophilous graphs. To address this issue, we propose a novel classifier, Label Context Classifier (LCC), designed to capture higher-order class la
Unsupervised Continual Learning (UCL) aims to enable neural networks to learn sequential tasks without labels or access to past data. A major challenge in this setting is Catastrophic Forgetting, where models forget previously learned tasks upon learning new ones. This challenge is amplified in UCL due to the absence of labels to guide learning and memory retention. Existing mitigation strategies, such as knowledge distillation and replay buffers, often raise memory and privacy concerns. Moreover, current UCL methods largely overlook clustering-specific objectives. To fill this gap, we introduce Unsupervised Continual Clustering (UCC) and propose Forward-Backward Knowledge Distillation for C
Turkish idiomatic light verb constructions (LVCs) are challenging for multiword expression processing because they often share the same surface form as fully literal verb-object combinations while functioning as a single, partially idiomatic predicate. We frame Turkish LVC detection as a binary classification task (literal meaning vs. idiomatic meaning) and evaluate on a manually created controlled set (N=147) with matched negatives: out-of-domain random sentences and in-domain literal controls (NLVC), alongside LVC positives. We compare a supervised Turkish encoder baseline (BERTurk with a classifier head) to three instruction-tuned LLMs from different families under zero-shot, one-shot, an
While Computational Fluid Dynamics (CFD) provides high-fidelity flow fields for optimizing indoor environments, its computational cost limits rapid exploration. To solve this problem generative surrogates offer better distribution modeling than deterministic networks, but iterative sampling is slow. To enable high-quality, single-pass generation, we adapt the novel generative drifting framework to fluid mechanics. We introduce a conditional architecture that performs drifting in a learned VAE latent space and uses label-aware masking to align generated samples with their boundary conditions. Our label-conditioned model matches iterative diffusion in accuracy and flow consistency while runnin
Many important outcomes unfold as dynamic cascades, including product adoption, disease spread, financial distress, and information diffusion. A central challenge is to recover the hidden influence network behind these cascades. Existing methods typically assume a specific diffusion model, and their performance degrades substantially when that assumption is misspecified. We propose CascadeNet, a Jacobian-based machine learning framework for network recovery that does not require specifying a diffusion mechanism. The key idea is that the underlying influence structure can be characterized by the Jacobian of the one-step transition function. CascadeNet first constructs a flexible estimator of
Personalized virtual heart simulations face challenges in model personalization and computational cost. While neural surrogates offer state-of-the-art solutions, they typically address either efficient personalization or training generalizable models. Recent work reframes this by learning the process of personalizing a surrogate using limited subject-specific context data, through few-shot generative modeling with set-conditioned surrogates and meta-learned amortized inference. These methods, however, assume a static and diverse training distribution with known task identifiers. When new data becomes available, they require costly retraining with all prior data to avoid catastrophic forgetti
Frontier AI systems are bridging the gap between intelligence and utility by shifting from conversational assistants to autonomous agents that execute tasks end to end. Using production data from Perplexity's Search and Computer products, we study this transition by examining how AI agents accelerate and reshape knowledge work. Three key empirical findings emerge. First, using sessions with near-identical initial query pairs as natural experiments for the same underlying task attempted with both products, Computer performs 26 minutes of autonomous work per user session, versus 33 seconds for Search. Computer automates task decomposition and execution that Search users might otherwise manuall
High-performance computing (HPC) clusters remain the backbone of large-scale scientific computation, traditionally executing deterministic, linear pipelines optimised for predictable performance. However, the pervasive integration of artificial intelligence (AI) and foundation models into scientific research has introduced a fundamentally new computational paradigm. AI-driven workflows are characteristically iterative, data-driven, and probabilistic, introducing unique challenges regarding data gravity, heterogeneous resource management, and complex workflow orchestration. This guide provides twelve practical tips designed to help researchers design efficient, scalable, and reproducible AI-d
The ranking of recommendation algorithms is a challenging problem since model performance is sensitive to dataset characteristics such as sparsity, sequential structure, and scale. This drives a demand for a proper methodology for fair comparison between algorithms. Naive aggregation of performance metrics (e.g., averaging NDCG over benchmarks) can yield misleading rankings, undermining practical selection. To address this problem, we introduce a novel, data-driven ranking methodology based on Bradley-Terry (BT) model. We demonstrate that the obtained ranking depends on key dataset statistics. Additionally, we propose a novel metric for evaluating ranking consistency and demonstrate robustne
Understanding how training data shape neural network predictions is a central problem in modern learning theory. In 2020, Pedro Domingos proposed an interpolation formula valid for every model learned by deterministic gradient descent. It expresses the model's prediction as an integral, along the optimization path, of a data-dependent kernel that aligns the model's gradients at the test and training data. Such a first-order characterization remains valid for models trained with batch-based stochastic optimization. In this paper, we develop second-order forms of these interpolation formulas. We show that the leading path-kernel interpolation is supplemented by a curvature-weighted interpolati
Decentralized stochastic optimization is a fundamental paradigm for large-scale learning over networks, where agents communicate only with their neighbors and no central coordinator is required. For strongly convex problems, communication efficiency is mainly determined by the condition number \(κ=L/μ\) and the network spectral gap \(1-β\). Although deterministic decentralized methods can simultaneously achieve accelerated \(\sqrtκ\) and \(1/\sqrt{1-β}\) dependences, no existing stochastic method attains both improvements at once. In this paper, we propose \emph{Multi-Gossip Accelerated DSGD} (MG-ADSGD), a decentralized stochastic algorithm that combines Nesterov-type primal--dual extrapolat
Continual learning in Large Language Models (LLMs) is hindered by the plasticity-stability dilemma, where acquiring new capabilities often leads to catastrophic forgetting of previous knowledge. Existing methods typically treat parameters uniformly, failing to distinguish between specific task knowledge and shared capabilities. We introduce Mixture of Sparse Experts for Task Agnostic Continual Learning (SETA), a framework that resolves the plasticity-stability conflict through adaptive sparse subspace decomposition into task-specific expert modules. Unlike standard updates, where tasks compete for the same parameters, SETA separates knowledge into unique experts, designed to isolate task-spe
Large language models exhibit impressive zero-shot capabilities across a wide range of downstream tasks. However, they struggle to function as off-the-shelf embedding models, leading to suboptimal performance on massive text embedding benchmarks. In this paper, we identify a potential cause underlying this deficiency. Our motivation stems from an unexpected observation: text embeddings tend to align with frequent but uninformative tokens when projected onto the vocabulary space. We argue that this excessive expression of high-frequency tokens suppresses the model's ability to capture nuanced semantics. To address this, we introduce EmbedFilter, a simple linear transformation designed to refi
Current Vision-Language Models struggle with hours-long videos because processing full-length visual sequences induces prohibitive token explosion and attention dilution. To overcome this, we introduce MemDreamer to decouple perception and reasoning, shifting long-video understanding into an agentic exploration process. As a plug-and-play framework, it incrementally streams videos to construct a Hierarchical Graph Memory, a top-down three-tier architecture for semantic abstraction, anchored by a foundational graph capturing spatiotemporal and causal relations. During inference, the reasoning model employs agentic tool-augmented retrieval, navigating hierarchies, searching nodes, and traversi
Humans learn from social life. Simulating this process with LLM-powered agents represents a promising research direction, raising a natural question: whether LLMs can learn from such simulated social experience to better understand and replicate human behavior. However, prior agent society simulations typically operate at the scale of days, limiting the depth of social interactions and long-term growth. In this paper, we study long-term life simulation and LLM learning in agent societies, with two goals: (1) investigating social behaviors that emerge from life-long simulation, and (2) developing anthropomorphic capabilities in LLMs, particularly intelligence in social life, through years of
We investigate the probabilistic reasoning capabilities of large language models through a controlled benchmarking study on discrete probability problems. We constructed two datasets, respectively a set of standard exercises and a set of counterintuitive exercises, designed to trigger heuristic reasoning, and evaluated 8 state-of-the-art models, each tested with and without Chain-of-Thought prompting. Models achieve an average accuracy of 0.96 on standard problems but only 0.59 on counterintuitive ones. We further provide empirical evidence of token bias: performance drops by over 20% when canonical formulations are replaced by disguised variants. Embedding misleading suggestions in the prom
Investment index
NVIDIA / AMD / Broadcom / TSMC / ASML / Arm
Accelerator supply, networking, packaging, and utilization remain the central AI bottleneck.
Microsoft / Amazon / Google / Oracle / CoreWeave
Distribution and committed capacity shape which model companies can scale.
OpenAI / Anthropic / Perplexity / Runway / Harvey
The application layer is splitting into consumer assistants and vertical workflow systems.
Utilities / Data centers / Cooling / Storage / Networking
Power contracts and data center approvals are turning into AI growth indicators.
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